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| US Open | ||
| Surface: Hard | Date: Aug. 27 - Sep. 9 | Seed: 30 |
| Round | Opponent | W / L | Result |
| First Round | Nicole Gibbs | Win | 5-7, 6-3, 6-4 |
| Second Round | Kristina Mladenovic | Win | 6-1, 4-6, 6-4 |
| Third Round | Caroline Garcia | Win | 5-7, 6-4, 7-6 (7-4) |
| Fourth Round | Maria Sharapova | Win | 6-4, 6-3 |
| Quarterfinals | Madison Keys | Loss | 4-6, 3-6 |
| Connecticut Open presented by United Technologies | ||
| Surface: Hard | Date: Aug. 19 - Aug. 25 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Barbora Strycova | Win | 7-6 (8-6), 6-4 |
| Second Round | Johanna Konta | Win | Retired |
| Quarterfinals | Petra Kvitova | Win | 6-3, 0-0 Retired |
| Semifinals | Monica Puig | Win | 4-4 Retired |
| Final | Aryna Sabalenka | Loss | 1-6, 4-6 |
| Western & Southern Womens Open | ||
| Surface: Hard | Date: Aug. 12 - Aug. 19 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Victoria Azarenka | Loss | 7-6 (7-5), 2-6, 4-6 |
| Coupe Rogers presentee par Banque Nationale | ||
| Surface: Hard | Date: Aug. 6 - Aug. 12 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Naomi Osaka | Win | 7-6 (7-2), 6-2 |
| Second Round | Lesia Tsurenko | Win | 6-4, 3-2 Retired |
| Third Round | Sloane Stephens | Loss | 2-6, 5-7 |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 2 - Jul. 15 | Seed: 27 |
| Round | Opponent | W / L | Result |
| First Round | Carina Witthoeft | Win | 6-2, 6-4 |
| Second Round | Sara Sorribes Tormo | Win | 6-4, 6-1 |
| Third Round | Belinda Bencic | Loss | 1-6, 6-7 (3-7) |
| Nature Valley International | ||
| Surface: Grass | Date: Jun. 24 - Jun. 30 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Danielle Collins | Loss | 2-6, 4-6 |
| Mallorca Open | ||
| Surface: Grass | Date: Jun. 18 - Jun. 24 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Lara Arruabarrena | Loss | 4-6, 6-7 (4-7) |
| Roland Garros | ||
| Surface: Red Clay | Date: May 27 - Jun. 10 | Seed: 23 |
| Round | Opponent | W / L | Result |
| First Round | Ana Konjuh | Win | 6-0, 6-1 |
| Second Round | Maria Sakkari | Loss | 5-7, 3-6 |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 13 - May 20 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Donna Vekic | Loss | 1-6, 2-6 |
| Mutua Madrid Open | ||
| Surface: Red Clay | Date: May 5 - May 13 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Barbora Strycova | Win | 6-3, 6-3 |
| Second Round | Elina Svitolina | Win | 2-6, 7-6 (7-3), 6-4 |
| Third Round | Bernarda Pera | Win | 2-6, 6-2, 6-4 |
| Quarterfinals | Caroline Garcia | Loss | 2-6, 3-6 |
| Porsche Tennis Grand Prix | ||
| Surface: Clay | Date: Apr. 23 - Apr. 29 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Veronika Kudermetova | Loss | 6-7 (5-7), 2-6 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 20 - Apr. 1 | Seed: 27 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Yafan Wang | Loss | 5-7, 3-6 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 7 - Mar. 18 | Seed: 27 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Su-Wei Hsieh | Win | 6-4, 2-6, 6-3 |
| Third Round | Elina Svitolina | Win | 7-5, 6-3 |
| Fourth Round | Danielle Collins | Win | 6-2, 6-4 |
| Quarterfinals | Venus Williams | Loss | 3-6, 2-6 |
| Dubai Duty Free Tennis Championships | ||
| Surface: Hard | Date: Feb. 19 - Feb. 24 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Sofya Zhuk | Win | 6-2, 6-2 |
| Second Round | Karolina Pliskova | Loss | 7-5, 2-6, 4-6 |
| Qatar Total Open | ||
| Surface: Hard | Date: Feb. 12 - Feb. 18 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Kateryna Bondarenko | Win | 3-6, 6-3, 6-3 |
| Second Round | Johanna Konta | Loss | 2-6, 2-6 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 15 - Jan. 28 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Magdalena Frech | Win | 7-5, 6-3 |
| Second Round | Timea Babos | Win | 6-4, 2-6, 6-2 |
| Third Round | Kaia Kanepi | Win | 3-6, 6-1, 6-3 |
| Fourth Round | Anett Kontaveit | Win | 4-6, 6-4, 8-6 |
| Quarterfinals | Caroline Wozniacki | Loss | 0-6, 7-6 (7-3), 2-6 |
| Brisbane International presented by Suncorp | ||
| Surface: Hard | Date: Dec. 31 - Jan. 7 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Elina Svitolina | Loss | 2-6, 4-6 |
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